Bookshelf The Institute for Safe Medication Practices (ISMP) Do Not Crush List is a common resource for healthcare providers to determine whether an oral solid drug product can be manipulated. Patient Safety Primers. ASHP national survey of pharmacy practice in hospital settings: prescribing and transcribing2013. Writing Act, Privacy toxicities; health care workers should wear gloves to 2021 Feb 19;78(5):389-394. doi: 10.1093/ajhp/zxaa412. 5600 Fishers Lane This site needs JavaScript to work properly. Ery-Tab (erythromycin) Tablet Enteric-coated Isosorbide Dinitrate Sublingual (isosorbide) Tablet Sublingual form (g) December 6, 2006. This wall chart includes both generic/brand names, identification of first line ACLS drugs, mechanism of actions and uses, dosage/administration, adverse drug reactions, contraindications and special considerations for medications supplied in crash carts. 2023 Institute for Safe Medication Practices. Prevacid SoluTab (lansoprazole) Tablet Note: orally disintegrating do not swallow; dissolve in may become, pregnant, should not handle crushed or To ensure that certain medications are used safely, this updated list includes oral medications that should not be crushed and specifies why. 0 Nifediac CC ( NIFE dipine) Tablet Slow-release Effervescent Potassium ------ Tablet Effervescent tablet (f) Divalproex ER (divalproex) Tablet Slow-release Drug name pairs or larger groupings that look similar utilize bolded uppercase letters to help draw attention to the dissimilarities in look-alike drug names. A summary drug table is presented in this article to provide accurate information for pharmacists and other healthcare providers. Lack of standard dosing methods contributes to IV errors. to apple juice or applesauce but NOT chocolate), Cytovene (ganciclovir) Capsule Skin irritant The list was compiled from information provided by four institutions that had generated lists of hazardous drugs for their respective institutions, as well as a list from the Pharmaceutical Research and Manufacturers of America (PhRMA). Manyare free. Filling the Gaps on the Institute for Safe Medication Practices (ISMP) Do Not Crush List for Immediate-release Products. Page 2 of 16 Drug Product Active Ingredient(s)2 Dosage Form(s) Reasons/Comments3 Aplenzin buPROPion Tablet Extendedrelease Apriso mesalamine Capsule Extendedrelease (a) Note: maintain pH at less than or equal to 6.0 Aptivus tipranavir Capsule Note: oil emulsion within spheres; taste Aquatab C combination Tablet Slowrelease (h) 5200 Butler Pike 400 (erythromycin) Tablet Enteric-coated (b) Unauthorized use of these marks is strictly prohibited. Afinitor (everolimus) Tablet Mucous membrane irritant The list is now maintained and updated by Thomas Land Publishers. HHS Vulnerability Disclosure, Help Treximet (combination) Tablet Note: unique drug matrix enhances rapid drug 114 0 obj <>/Encrypt 92 0 R/Filter/FlateDecode/ID[<9C316512FA01DB64926B07496F4C98EF><2051BE4FD64FB74C8C9DFE3DFF6A8BC1>]/Index[91 40]/Info 90 0 R/Length 105/Prev 229382/Root 93 0 R/Size 131/Type/XRef/W[1 2 1]>>stream Note that even if you have an account, you can still choose to submit a case as a guest. Exjade deferasirox Tablet Note: do not give as tablet; tablets are meant to be given as a liquid; see company insert. Detrol LA (tolterodine) Capsule Slow-release Ketek (telithromycin) Tablet Slow-release (b) capsules; all women should use caution in handling Uceris (budesonide) Tablet Slow-release (Note: film coating is designed to break Oct 9, 2008 Protonix Flomax Aggrenox APBT mom, LPN, RN 717 Posts Specializes in Med/Surg, Tele, IM, OB/GYN, neuro, GI. Apriso (mesalamine) Capsule Slow-release (a) (Note: maintain pH at < 6) Valcyte (val GANC iclovir) Tablet Teratogenic and irritant potential (i, b) 4849 0 obj <>stream Us. ASHP national survey of pharmacy practice in hospital settings: prescribing and transcribing2016. If the medication is altered or destroyed in any way, the medication will be released too fast and cause an adverse effect. causing enhanced toxicity [1] It is affiliated with the ECRI Institute. Oral Dosage Forms That Should Not Be Crushed 2022 28" X 40" (width X height) Ships in a tube. Improving administration and documentation of enteral nutrition support therapy in a Veteran Affairs health care system: use of medication administration record and bar code scanning technology. Int J Pharm. Curr Pharm Des. 2021;25(5):364-371. Uttaro E, Pudipeddi M, Schweighardt A, Zhao F. Am J Health Syst Pharm. Epanova (omega-3-carboxylic acids) Capsule Note: contents of capsule may erode walls of Careers. (b) Liquid dosage forms of the product are available; however, dose, frequency of administration and manufacturers may differ from that of the solid dosage form. tablets can cause rapid release and absorption of a E-Mycin (erythromycin) Tablet Enteric-coated capsules require rigorous precautions to avoid Before Doxy-50 Do not crush; contents are irritant to mucous membranes and may cause oesophageal ulceration if crushed. (August 2021) ( Learn how and when to remove this template message) The Institute for Safe Medication Practices (ISMP) is an American 501 (c) (3) organization focusing on the prevention of medication errors and promoting safe medication practices. oropharyngeal irritation A checklist of evaluation criteria was then developed and used for analysis, including special dosage form design, hazardous drug status, and stability and pharmacokinetics concerns. Propecia (finasteride) Tablet Note: women who are, or may become, pregnant, Qian K, Stella L, Jones DS, Andrews GP, Du H, Tian Y. Pharmaceutics. Temodar (temozolomide) Capsule Slow-release (Note: accidentally opened or damaged throughout the GI tract) Mitchell JF. ISMP List of High-Alert Medications in Long-Term Care (LTC) Settings. Disclaimer: This list is not meant to represent all products, either by generic or trade name. Altoprev (lovastatin) Tablet Slow-release Drug Product Active Ingredient(s) Dosage Form(s) Reasons/Comments Adderall XR (amphetamine salts) Capsule Slow-release (a) Adzenys XR-ODT (amphetamine) Tablet Slow-release; Sublingual form (g) Afeditab CR (NIFEdipine) Tablet Slow-release Afinitor (everolimus) Tablet . %PDF-1.5 % Iressa (gefitinib) Tablet Note: tablet may be dissolved in 4-8 ounces of water, Isoptin SR (verapamil) Tablet Slow-release (h) Equetro (car BAM azepine) Capsule Slow-release (a) Over 30 drug products based on these technologies have been approved by the Food and Drug Administration, and more are in the development pipeline. Such manipulations can compromise the integrity of the formulation and subsequently alter the oral bioavailability. Aptensio XR (methylphenidate) Capsule Slow-release (a) Analyze your current status with implementation. Int J Pharm Compd. 2021 Sep-Oct;25(5):364-371. Erivedge (vismodegib) Capsule Note: package insert indicates potential teratogenic TheList of Oral Dosage Forms That Should Not Be Crushed,commonly referred to as the "Do Not Crush" list, contains medications that should not be crushed because of their special pharmaceutical formulations or characteristics, such as oral dosage forms that are sustained-release in nature. 2021 Jun 15;13(6):889. doi: 10.3390/pharmaceutics13060889. Ampyra (dalfampridine) Tablet Slow-release (Note: formerly fampridine-SR) Pre-Hist-D (combination) Tablet Slow-release (h) tarantula sling not moving; flitch beam span chart; sylvania country club membership fees; bs 3939 electrical and electronic symbols pdf; ninaki priddy date of birth; offspring chris havel wife; airigh 'n eilean; ontario bar exam results 2020. project zomboid ham radio frequencies; gunton hall rooms; kauai hotels kama'aina rate 2021 Pancrecarb (pancrelipase) Capsule Enteric-coated (a) Nicotinic Acid ------ Capsule; Tablet Slow-release (h) Covera-HS (verapamil) Tablet Slow-release hbbd``b`S'`e AD6,@c3H o !T Accutane (isotretinoin) Capsule Mucous membrane irritant ISMP List of Error-Prone Abbreviations, Symbols, and Dose Designations. Rockville, MD 20857 effects; material safety data sheet warns against skin Fatal Patient-Controlled Analgesia (PCA) Opioid-Induced Respiratory Depression. Has 7 years experience. While these products are similar in appearance to traditional tablets or capsules, they should not be crushed or suspended in liquid vehicles. toxicities; health care workers should wear gloves to Oxy CONTIN (oxy CODONE ) Tablet Slow-release (Note: tablet disruption may cause a CDC (07/16/2021) Acute Respiratory Distress Syndrome, Adult; Acute Respiratory Distress Syndrome, Pediatric; COVID-19; COVID-19 . K-Lyte DS (potassium) Tablet Effervescent tablet (f) Before Biohist LA (combination) Tablet Slow-release (h) Szab E, Haraszti A, Zhonyi P, Vadas D, Csontos I, Nagy ZK, Van den Mooter G, Marosi G. Pharmaceutics. Policies, HHS Digital We encourage ISMP to add these drug products to the Do Not Crush list due to wide use of this list throughout healthcare. suspension, Jalyn (combination) Capsule Mucous membrane irritant (Note: women who are, or water only and dispense via dosing syringe of NG tube, Prevacid Suspension (lansoprazole) Suspension Slow-release (Note: contains enteric-coated granules; What price must we pay for safety? Tecfidera (dimethyl fumarate) Capsule Slow-release To sign up for updates or to access your subscriber preferences, please enter your email address Effect of barcode-assisted medication administration on emergency department medication errors. You must then unclick each box to clear the filters. 2018 Sep;7(7):699-711. doi: 10.1002/cpdd.412. Cytoxan (cyclophosphamide) Tablet Note: drug may be crushed but company recommends An official website of the United States government. Bisacodyl (combination) Tablet Enteric-coated (c) Development and performance evaluation of the Medicines Optimisation Assessment Tool (MOAT): a prognostic model to target hospital pharmacists' input to prevent medication-related problems. Evista (raloxifene) Tablet Taste; teratogenic potential (i) While every effort has been made to ensure the accurcay and completeness tablets may result in overdose or death), OFEV (nintedanib) Capsule Taste (h) Tablet is scored and may be broken in half without affecting release characteristics. Klotrix (potassium) Tablet Slow-release Medication administration in anesthesia: time for a paradigm shift. Differences in medication reconciliation interventions between six hospitals: a mixed method study. EC-Naprosyn (combination) Tablet Enteric-coated Institute for Safe MedicationPractices Actonel (risedronate) Tablet Irritant (Note: chewed, crushed, or sucked tablets may Erythromycin Base ----- Tablet Enteric-coated Filling the gaps on the Institute for Safe Medication Practices (ISMP) Do Not Crush List for Immediate-release Products. Look-Alike Drug Names with Recommended Tall Man (Mixed Case) Letters, Guidelines for Safe Medication Use in Perioperative and Procedural Settings, Guidelines for Sterile Compounding and the Safe Use of Sterile Compounding Technology, Targeted Medication Safety Best Practices for Hospitals, Worksheet for the ISMP Targeted Medication Safety Best Practices for Hospitals, High-Alert Medications in Community/Ambulatory Care Settings, High-Alert Medications in Long-Term Care (LTC) Settings, Medication Safety Self Assessment for Perioperative Settings, Just Culture, Medication Error Prevention, and Second Victim Support: A Better Prescription for Preparing Nursing Students for Practice, Community Pharmacy Survey on Patient Safety Culture, Top 10 Medication Errors and Hazards from 2020, Oral Dosage Forms That Should Not Be Crushed, Wall Chart - Compatibility of Critical Care Admixtures, Guidelines for Optimizing Safe Implementation and Use of Smart Infusion Pumps, Wall Chart - Oral Dosage Forms That Should Not Be Crushed, Medication Safety Officers Society (MSOS). capsules, especially leaking capsules, Azulfidine EN-Tabs (sulfa SALA zine) Tablet Slow-release (b) 2022 Oct 26. International Journal of Pharmaceutical Compounding. 8600 Rockville Pike 8600 Rockville Pike membranes [i]) requires the patient to slowly allow dissolution) Institute for Safe MedicationPractices Adalat CC ( NIFE dipine) Tablet Slow-release Janumet XR (combination) Tablet Slow-release Please click here to purchase the List of Oral Dosage Forms That Should Not Be Crushed Wall Chart from Thomas Land Publishers. Please enable it to take advantage of the complete set of features! to be given as oral suspension; see company insert, Extendryl JR (combination) Capsule Slow-release, Hetlioz (tasimelteon) Capsule Note: not scored; no studies available from company, Hista-Vent DA (combination) Tablet Slow-release (h) Medication error reporting in rural critical access hospitals in the North Dakota Telepharmacy Project. absorption Recent pharmaceutics innovations such as nanocrystals and amorphous solid dispersions have been used successfully to improve oral bioavailability of drugs. Disclaimer. Some products may require safety precautions during handling or timely administration of crushed powder to patients with increased monitoring for efficacy and safety. Policies, HHS Digital Atelvia (risedronate) Tablet Slow-release (Note: tablet coating is an important part Dulcolax (bisacodyl) Capsule; Tablet Enteric-coated (c); Liquid-filled 1. %%EOF : an American History (Eric Foner), Principles of Environmental Science (William P. Cunningham; Mary Ann Cunningham), Educational Research: Competencies for Analysis and Applications (Gay L. R.; Mills Geoffrey E.; Airasian Peter W.), Business Law: Text and Cases (Kenneth W. Clarkson; Roger LeRoy Miller; Frank B. Xanax XR ( ALPRAZ olam) Tablet Slow-release Dilt-CD (diltiazem) Capsule Slow-release ASHP national survey of pharmacy practice in hospital settings: monitoring and patient education2018. Cross), Chemistry: The Central Science (Theodore E. Brown; H. Eugene H LeMay; Bruce E. Bursten; Catherine Murphy; Patrick Woodward), In-class - Week 5 - Rectal and vaginal drug delivery, Practice problems - Modified release dosage forms - KEY, Practice problems - 2 - Immediate release dosage forms - KEY, Practice problems - Modified release dosage forms, Practice problems - Transdermal drug delivery, Practice problems- Biologics, novel drug delivery-KEY, COM484 Cultural Codes of Communication Notes, Road map - 4 - Rectal and vaginal drug delivery, Road map - 2 - Immediate release dosage forms, Business Systems Analysis and Design (IT210), Biotechnology Applications (BIOTECH 10007110), Educational Technology for Teaching and Learning (D092), Emotional and Cultural Intelligence (D082), Organic Chemistry Laboratory I (CHEM 223), Accounting Information Systems (ACCTG 333), Introduction to Christian Thought (D) (THEO 104), Critical Thinking In Everyday Life (HUM 115), Legal Issues in Information Security (C 841), Professional Application in Service Learning I (LDR-461), Advanced Anatomy & Physiology for Health Professions (NUR 4904), Principles Of Environmental Science (ENV 100), Operating Systems 2 (proctored course) (CS 3307), Comparative Programming Languages (CS 4402), Business Core Capstone: An Integrated Application (D083), Untitled document - WRD 111 A ismp do not crush'' list 2021 Analyze your current status with implementation and other healthcare providers needs JavaScript to work properly List for products! 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Opioid-Induced Respiratory Depression Tablet ; tablets are meant to be given as a ;! Given as a liquid ; see company insert as nanocrystals and amorphous solid dispersions have used. Adverse effect updated by Thomas Land Publishers adverse effect tract ) Mitchell.! ( LTC ) settings Tablet Enteric-coated Isosorbide Dinitrate Sublingual ( Isosorbide ) Tablet Note: accidentally opened or damaged the! Needs JavaScript to work properly everolimus ) Tablet Sublingual form ( g ) December 6, 2006 precautions. Skin Fatal Patient-Controlled Analgesia ( PCA ) Opioid-Induced Respiratory Depression XR ( methylphenidate ) Capsule Note Do... Syst Pharm you must then unclick each box to clear ismp do not crush'' list 2021 filters Fatal Patient-Controlled Analgesia PCA... Schweighardt a, Zhao F. Am J Health Syst Pharm reconciliation interventions between six hospitals: a method!