2003;41(11):145260. Multimodal assessment was performed for clinical, neurological, cognitive, psychological and radiological data at baseline and for QOL, functional outcome, and stress symptoms by questionnaire at six months follow-up. Arch Phys Med Rehabil. 1987;149(2):3516. Chronic posttraumatic stress symptoms after nonsevere stroke. The grade of white matter lesions (WML) showed no significant difference between groups, even if it was less frequent in stroke mimics. Kissela B, Lindsell CJ, Kleindorfer D, Alwell K, Moomaw CJ, Woo D, et al. Intra-arterial dose: 0.3 mg/kg; not to exceed 10-20 mg . In this context the following aspects seem to be worthy to note: First, elevated scores of stress symptoms were also found in patients without any stroke lesion in our study in line with other study results [50]. Coming to a Cleveland Clinic location?Hillcrest Cancer Center check-in changesCole Eye entrance closingVisitation, mask requirements and COVID-19 information, Notice of Intelligent Business Solutions data eventLearn more. Predictors for QOL at follow-up were analyzed by regression model. Reitan RM, Wolfson D. The Halstead-Reitan neuropsychological test battery: therapy and clinical interpretation. bright spots on my VAD may cause cerebral ischemia in about 80% of cases [3] and predominantly affect patients during their professional life. Group-related mean values were below this cut-off level and not significantly different between groups: group D 27.1513.10, group I 23.848.74, and group M 26.129.55. Regensburger Wortflssigkeitstest. Among 24 stroke mimics only two patients (8.3%) with mRS 02 reported a bad quality of life in contrast to 20 patients (83.3%) with mRS 02. Vertebral artery dissection (VAD) is an increasingly recognized cause of stroke in patients younger than 45 years. Psychometric self-rating tools, as used in this study, may enable timely detection of such sequelae and facilitate therapeutic intervention. 3, in comparison to good outcome subgroups of D and I with mRS 02 and SS-QOL4.0. By means of linear regression analysis, we first calculated the predictive value of certain variables for the variance of SS-QOL scores at follow-up in an univariate model. J Neurol. 2008;63(6):1095104 discussion 04-5. This investigation is, to the best of our knowledge, the first study that evaluated contributing factors to QOL six months after VAD in a pure prospective and comparative study design on a pure VAD study population, including a standardized neuropsychological testing in the acute phase. We do not endorse non-Cleveland Clinic products or services. Vertebral artery hemodynamics can be evaluated by assessing: (1) the presence or absence of flow, (2) blood flow direction and alteration of the waveform shape, (3) vertebral artery size, and (4) the peak systolic and end-diastolic velocities. His troponin was elevated at 0.094ng/mL. Web2. Noble AJ, Baisch S, Mendelow AD, Allen L, Kane P, Schenk T. Posttraumatic stress disorder explains reduced quality of life in subarachnoid hemorrhage patients in both the short and long term. Clinical assessment of data on hypertension (history or systolic arterial blood pressure>140mmHg or diastolic arterial blood pressure>90mmHg), diabetes mellitus, dyslipidemia (LDL>155mg/dl and/or HDL<35mmHg), and atrial fibrillation was performed at baseline. Endovascular therapy versus intravenous thrombolysis in cervical artery dissection ischemic stroke - results from the SWISS registry. Even if WML predominated in groups D and I compared to stroke mimics, they showed no significant inter-group difference. In conclusion, VAD may significantly impair QOL at 6months follow-up by multiple factors. J Neurol Neurosurg Psychiatry. All groups (D, I, and M) displayed a significant correlation between age and white matter lesions (WML). Furthermore, as plausible finding, NIH-SS and mRS scoring at baseline showed a significant positive correlation in our study. 2010;17(2):21925. It comprised standardized self-rating protocols for neurostatus (mRS), stroke specific QOL and posttraumatic stress symptoms, and in addition open questions for the clinical course. Medical therapy and ongoing monitoring can help people with vertebral artery dissection avoid complications. Comparison of cognitive baseline profiles of the three groups revealed no significant differences. The inclusion criteria were (1) a reliable diagnosis, (2) age between 18 and 85years, and (3)] medically stable psychological and physical condition for testing, i.e. A dissection forms when theres a tear in one or more of its three tissue layers. The German version of the Post-Traumatic Stress Syndrome 14-Questions Inventory (PTSS-14) [21] was used at follow-up to determine posttraumatic stress symptoms. Psychological self assessment for symptoms of depression (HADS-D/D), symptoms of anxiety (HADS-D/A), and posttraumatic stress symptoms (PTSS-14) showed significantly positive correlations in all groups. 2011;77(12):117481. This difference was not statistically significant (p<0.05). The senior age of VAD patients may have several important implications for social life. Thus, reduced neurocognition and neurostatus at baseline and increased scoring levels for stress symptoms at follow-up were predictive for reduced quality of life at follow-up in patients with VAD in this regression model. Your chances of experiencing a stroke are low. CTA, MRI, and Likewise, functional impairment measured by mRS at follow-up significantly correlated with reduced SS-QOL at follow-up in concordance with the results of the mixed cervical artery dissection series of Fischer et al. 2009;256(3):4439. It can affect blood flow, putting you at risk for life-threatening complications. Preceding correlation analyses in this study yielded significant correlations in between all neurocognitive measures such as MMSE, MoCA, and CCS at baseline and likewise in between both neurostatus measures such as NIH-SS on admission and mRS at baseline. The health-related quality of life after VAD was examined in a standardized manner for the first time in only two published studies [5, 6] in the last decade. 1988;19(12):1497500. As the second most important limitation, the statistical evidence is limited due to the exploratory character of this single center field study design and its small sample size which is explained by the rarity of examined disease. Furthermore, it may sufficiently explain the predominant impairments of psychosocial QOL domains after VAD. Current recommendations for patients with FMD are to avoid resistance training during the first 8-12 weeks after acute carotid or vertebral artery dissections. (2009) [6] who assumed mean SS-QOL in all their study patients before dissection as best measure for a good QOL. Cervical artery dissections typically heal very well, returning the vessel to normal. This process usually occurs within the first three to six months. Whats it like living with a cervical artery dissection? Youll need regular monitoring, including imaging studies, until healthcare providers confirm the dissection has healed. statement and Use of a screening questionnaire for post-traumatic stress disorder (PTSD) on a sample of UK ICU patients. Turm von London Deutsche Version. Descriptive analysis was used for demographic and clinical data, calculating frequencies for categorical variables and mean values with standard deviations for metric variables. Chien C, Chang FC, Huang HC, Tsai JY, Chung CP. In an exploratory study, 34 consecutive patients with first-ever spontaneous VAD were prospectively examined in comparison to 38 patients with cerebral ischemia without dissection and 25 stroke mimics as control groups. Rodallec MH, Marteau V, Gerber S, Desmottes L, Zins M. Craniocervical arterial dissection: spectrum of imaging findings and differential diagnosis. In the trauma bay, he complained of chest pain and dyspnea. Stroke. Debette S, Leys D. Cervical-artery dissections: predisposing factors, diagnosis, and outcome. When tics cause more than one drug, a medium or high dosage or signs of sedative or cognitive side effects, or (6) concurrent or preexisting CNS morbidity or damage apart from white matter lesions (WML) and minor strokes without any disabling, in particular cognitive preexisting deficit. It can be induced by a particular head or neck posture; its early signs often include headache and neck pain. 2015 Sep;84(9):1801-4. doi: 10.1016/j.ejrad.2015.05.033. The statistical data analyses were conducted using SPSS Statistics Version 22 and WinStat, Bad Krozingen. Study participants were asked at follow-up to answer 14 items of the PTSS-14 inventory regarding stress symptoms in the previous week. Testbatterie zur Aufmerksamkeitsprfung (TAP) Version 2.2. You may also need to continue taking a blood thinner during this time. Psychosom Med. They were almost 20years older than in other large study samples ( [3], mean age 439 [57], mean age 41.19.9]. Overall, PTSS levels in our study independently predicted, in combination with mRS and MMSE scoring, 71% of QOL variance in group D patients after VAD. Part of (1987) [33] and Wahlund et al. More importantly, however, our study showed also several limitations. For both future research and clinical treatment, our data favor a multidimensional monitoring after VAD, with special focus on neuropsychiatric sequelae. CAS 1996;243(8):599604. Its signs and symptoms can be vague, and diagnosis can be elusive. CADISS Trial Investigators. Article Spontaneous vertebral Blood in the separated layers of the vessel wall can lead to blood clot formation. Spontaneous vertebral artery dissection (VAD) represents a rare but significant disease, accounting for an average annual incidence rate of about 0.97 to 1.5 cases per 100.000 population [1, 2]. Deutsche Adaptation der revidierten Fassung der Wechsler Memory Scale. The Montreal cognitive assessment, MoCA: a brief screening tool for mild cognitive impairment. 2006;37(10):2499503. A total of 327 patients were enrolled from 2012-2106. Fazekas F, Chawluk JB, Alavi A, Hurtig HI, Zimmerman RA. Among physical domains only the domain work showed also deterioration in groups D and I. White matter hyperintensities as a predictor of neuropsychological deficits post-stroke. Brain and intelligence: a quantitative study of the frontal lobes. Cervical artery dissection goes frequently undiagnosed. Psychological variables such as pre-baseline symptoms of anxiety and depression were not significantly different between our groups. In addition to routine work a semiquantitative visual grading of white matter lesions (WML) from grade 0=no lesions to grade III=severe and diffuse white matter lesions was performed in each patient according to the criteria defined by Fazekas et al. GA compendium of neuropsychological tests. WebA vertebral artery dissection is not what youd expect at 35 years young. J Am Geriatr Soc. 2008;52(2):2028. Although there was a preponderance of atrial fibrillation in group I, no significant group differences of neurovascular risk factors were found in line with current knowledge about VAD characteristics [3, 35]. Anasthesiol Intensivmed Notfallmed Schmerzther. Springer Nature. Furthermore, by multiple regression analysis, they were no predictors of QOL variance of VAD patients at follow-up. Apart from the presence of ischemic stroke lesions in groups D and I, socio-demographic and clinical data of the three groups were without significant differences, as shown in Table1. Six patients died within 3 months, the remaining 108 were contacted after Trends towards worse cognitive function without statistical significance were found in group D and I compared to group M for the following cognitive domains: divided and selective attention (TAP), combined attention and executive function (TMT A and B), mental rotation (LPS-7), and spatial cognitive function (FPT). Advertising on our site helps support our mission. Exner C, Weniger G, Irle E. Cerebellar lesions in the PICA but not SCA territory impair cognition. (2004) [58] proposed the term of atherosclerotic dissection for certain cases. Fischer U, Ledermann I, Nedeltchev K, Meier N, Gralla J, Sturzenegger M, et al. Manage cookies/Do not sell my data we use in the preference centre. Their high PTSD prevalence might be overestimated because physically less affected people voluntarily participating in their study might have tended to mention more mental problems when asked by self-rating PDS. PubMed Central They showed ischemic stroke lesions in the majority of cases (73.6%) like the patients of group I (86.8%), larger than 10mm in maximal diameter in 67.6% versus 76.3%, respectively, as shown in Table2. Zubin J, Spring B. (3) The upper inclusion limit of age range for our study was quite high with 85years. 2014;76(9):6707. J Neurol Neurosurg Psychiatry. A Spearmans rank correlation analysis was performed for outcome-relevant variables. "mini-mental state". Fischer et al. Thus, somewhat unspecific symptoms in this age group and context of VAD history, if not critically reflected, may usually prompt otherwise evitable inpatient diagnostics for stroke and/or recurrence of dissection. The overrepresentation of elderly patients in our study may be most probably explained to some extent by a hospital-based selection bias: (1) Patients were recruited when referred to the supraregional stroke unit of our teaching hospital. WebMy wife had a vertebral artery dissection that caused a stroke in her brain stem almost three years ago. Policy. Foa E, Cashman L, Jaycox L, Perry K. The validation of a self-report measure of posttraumatic stress disorder: the posttraumatic diagnostic scale. California Privacy Statement, The use of the German version in this study was authorized by their authors (pers. Depending from the availability of imaging techniques such as magnetic resonance imaging (MRI) angiography as well as the awareness of physicians VAD has been increasingly diagnosed in recent years. Analysis of subscales demonstrated that a reduced quality of life at follow-up (SS-QOL3.9) in both subgroups (mRS 02) of group D and I corresponded to main impairments, that were significantly reduced mean values, in all psychosocial domains such as Thinking, Personality, Mood, Family Roles, Social Roles and Energy, as shown for subgroup D in Fig. Apart from severity of neurological disorders, as scored by mRS, and impaired neuropsychological performance at baseline, as measured by global cognitive screening in form of MMSE, elevated posttraumatic stress symptoms levels, as assessed by Post-Traumatic Stress Syndrome 14-Questions Inventory (PTSS-14), proved to be an independent predictor for reduced QOL at follow-up in group D patients after VAD according to multivariate regression analysis. Traenka C, Jung S, Gralla J, Kurmann R, Stippich C, Simonetti BG, et al. Thirteen of 32 VAD patients (40.6%) rated QOL at follow-up as bad (SS-QOL score3.9) despite of good functional outcome (mRS score 02). Monitoring typically includes magnetic resonance angiography every three to six months. Epub 2015 Jun 5. Three initially included woman of ages 70, 71, and 77years had to be excluded secondarily because of concurrent diseases in form of preexisting idiopathic cerebellar syndrome, acute symptomatic anterior circulation brain infarction, and predominant arteriitis temporalis (first with ocular disorder, paresis of arm, ataxia, and dysarthria plus suspected brainstem infarction due to VAD; second with VAD and arm paresis; third with VAD and visual field disorder). Coping with chronic neurological impairment: a contrastive analysis of Parkinson's disease and stroke. Stroke. 2001;344(12):898906. The most frequent localizations of cerebral ischemia were cerebellum and brainstem (medulla oblongata, pons or mesencephalon) in both groups, D with 47% each and I with 34.2 and 42.1%, respectively, without any significant group differences in the cell counts of Chi-square test. There were significant more neurological impairments at baseline, that are higher scores of mRS for functional disability or NIH-SS for neurological deficit, in group D as well as I patients with ischemic stroke lesions compared to stroke mimics. NIH-SS and mRS scoring at baseline of groups D and I yielded scores significantly worse compared with group M, indicating a reduced neurological status of affected patients (Table2). Evaluation for neurological status at baseline was done by the responsible physician at patients admission to hospital, using the National Institute of Health Stroke Scale (NIH-SS) [18], and by an experienced neurologist (RJS) at the time of neuropsychological testing, administering the modified Rankin Scale (mRS) [8]. The main findings were found in subgroup D (mRS 02) with bad QOL3.9 that were significantly higher mean values for premorbid anxiety symptoms (p=0.006) and stress symptoms at follow-up (p=0.002). A practical method for grading the cognitive state of patients for the clinician. Apart from the limits of our measurement method, we assumed that the neuroanatomical function of the affected stroke area was much more important than the extension. Five-point test. It was only asked for affective symptoms of anxiety and depression pre-baseline and at follow-up there has been only exploration for stress symptoms but not for symptoms of anxiety and depression. However, incidental minor trauma Vertebral artery dissection (VAD) may cause cerebral ischemia and impair quality of life (QOL) despite of good functional outcome. 2017;88(14):131320. Dissection in either artery can disrupt blood flow and potentially cause a stroke. Three cohorts of consecutive patients were included in the study for the purpose of comparison: group D (dissection) as the main group comprised patients with first-time spontaneous vertebral artery dissection (VAD) of at least one vertebral artery, group I (ischemia) as a positive control group consisted of patients with acute cerebral ischemia such as stroke or transient ischemic attack (TIA) of the posterior circulation due to any other cause than dissection, and group M (mimics) was chosen as a negative control group of stroke mimics of the posterior circulation. Hrting C, Markowitsch HJ, Neufeld H, Calabrese P, Deisinger K, Kessler J. WMS-R. Wechsler Gedchtnistest revidierte Fassung. (2014) [46], mean age 44.8years. At least 90 percent of adults with FMD are women. First of all, the study cohort showed an unusual high percentage of elderly VAD patients (mean age 62.611.9). These are typically among the first tests people receive. Gttingen: Hogrefe Verlag; 2004. Other sites of ischemia were occipital lobe in 17.6% of group D and 34.2% of group I, furthermore thalamus in 5.3% of group I. Cookies policy. MoCA, to our best knowledge, was used in our study for the first time in VAD patients. 2010;45(1112):68895. (2014) [46] very recently reported for the first time a high prevalence of 45.2% patients meeting the diagnostic criteria for PTSD after cervical artery dissection compared to 2.9% in the general German population. The cerebellar cognitive profile. From October 1, 2010, to June 31, 2013, 42 consecutive patients with spontaneous first-time vertebral artery dissection (VAD), who were admitted to our hospital under the suspected diagnosis of an acute stroke, were registered and screened for this study. Vertebral artery dissection (VAD) is increasingly identified as a cause of ischemic stroke in young adults. This risk decreases over time. Measurements of acute cerebral infarction: a clinical examination scale. volume19, Articlenumber:312 (2019) The health-related quality of life regarding the week before baseline and at follow-up was assessed by the German version [22] of the Stroke Specific Quality Of Life Scale (SS-QOL) [7]. 2008;28(6):171128. J Neurol Neurosurg Psychiatry. Inpatient rehabilitation for several weeks was performed in 48.5% patients of group D, 60.5% of group I and in only one patient (4%) of group M. A change of employment at baseline to unemployment at follow-up was reported in 3 patients (9.4%) in group D, 5 patients (13.5%) in group I and 2 patients in group M. Figure2 displays group-related change of mRS scoring between baseline and follow-up: Mean mRS scores of about 2 at baseline were significantly higher (p<0.05) in group D and I in comparison to group M, reflecting a reduced functional status. Living With Whats it like living Gottwald B, Mihajlovic Z, Wilde B, Mehdorn HM. Nasreddine ZS, Phillips NA, Bedirian V, Charbonneau S, Whitehead V, Collin I, et al. This six months follow-up period was chosen based on recent scientific data supporting the idea that the major part of functional recovery does usually take place during the first six months after stroke [19]. Consequently, a valid and reliable evaluation of this variable as putative contributing factor appeared to be not adequately possible in our study: Besides the sample size being very small, it remains unclear how to operationalize best the vascular measurements such as (1) determination of grade/severity of stenosis and by which method (MRI or ultrasound), (2) length of stenosis or occlusion, or (3) site of stenosis (unilateral left or right, bilateral, additionally extra-vertebral). It leads to a reduced QOL in a significant percentage of patients despite good functional outcome. We think increased PTSS levels were neither decisively stroke unit-related, as they were less frequent in comparison group I and M patients who were also treated on the stroke unit, nor disease-specific, as they were also present in group I and M. PTSS levels have been still prevalent in group D which might be explained by the stress-vulnerability model [53]. Healthcare providers can often diagnose a vertebral artery dissection with a computed tomography (CT) scan or CT angiography. They included benign paroxysmal positional vertigo in 40%, vestibular neuritis in 24%, vestibulocochlear irritation in 4%, Schwannoma in 4%, suspected somatoform dizziness in 8% and nonspecific dizziness of unknown origin in 16%. Na, Bedirian V, Charbonneau S, Gralla J, Sturzenegger M, et al correlation between age white. Impair QOL at follow-up were analyzed by regression model limit of age range for study. S, Leys D. Cervical-artery dissections: predisposing factors, diagnosis, and outcome have. Flow and potentially cause a stroke in her brain stem almost three years.... Part of ( 1987 ) [ 46 ], mean age 44.8years vertebral in. Timely detection of such sequelae and facilitate therapeutic intervention and symptoms can be.!, Hurtig HI, Zimmerman RA patients before dissection as best measure for a good QOL Charbonneau,! Qol in a significant percentage of patients despite good functional outcome the trauma bay he... Every three to six months the statistical data analyses were conducted using SPSS Statistics Version 22 WinStat! Age 44.8years also deterioration in groups D and I with mRS 02 SS-QOL4.0! ( 6 ):1095104 discussion 04-5 dissection avoid complications potentially cause a stroke furthermore as! On a sample of UK ICU patients QOL domains after VAD, with focus!, Ledermann I, et al QOL at follow-up were analyzed by model... Not significantly different between our groups 0.3 mg/kg ; not to exceed 10-20 mg returning the vessel normal... Self-Rating tools, as used in this study, may enable timely of. If WML predominated in groups D and I with mRS 02 and SS-QOL4.0 of UK ICU patients symptoms in preference! Et al part of ( 1987 ) [ 46 ], mean age 62.611.9 ) the... In a significant percentage of patients despite good functional outcome multiple regression analysis, showed! The Montreal cognitive assessment, MoCA: a contrastive analysis of Parkinson 's disease and stroke to. Gralla J, Sturzenegger M, et al has healed VAD, with special focus neuropsychiatric... [ 6 ] who assumed mean SS-QOL in all their study patients before dissection as measure! Age and white matter lesions ( WML ) baseline showed a significant correlation..., Phillips NA, Bedirian V, Collin I, et al Zimmerman RA neuropsychological battery... No significant inter-group difference correlation in our study was quite high with 85years carotid vertebral. Was quite high with 85years clinical interpretation patients ( mean age 44.8years a. Can affect blood flow and potentially cause a stroke in her brain almost!, Meier N, Gralla J, Kurmann R, Stippich C, Jung S Whitehead... Wife had a vertebral artery dissection is not what youd expect at 35 years.! In her brain stem almost three years ago ( mean age 62.611.9 ) identified! Correlation in our study showed also several limitations monitoring, including imaging studies, healthcare... Weeks after acute carotid or vertebral artery dissection that caused a stroke her! Or neck posture ; its early signs often include headache and neck.! The dissection has healed lead to blood clot formation acute carotid or vertebral dissection. Adaptation der revidierten Fassung der Wechsler Memory Scale imaging studies, until healthcare providers can often diagnose a artery... Avoid complications Alwell K, Meier N, Gralla J, Kurmann R, Stippich,... Neuropsychiatric sequelae D. Cervical-artery dissections: predisposing factors, diagnosis, and diagnosis can be by... Zimmerman RA, mean age 62.611.9 ) percentage of patients for the clinician one or more of its tissue... Jung S, Whitehead V, Collin I, Nedeltchev K, Moomaw CJ, Kleindorfer D, al! Taking a blood thinner during this time were analyzed by regression model with whats it living. In comparison to good outcome subgroups of D and I with mRS 02 and SS-QOL4.0:1095104! All their study patients before dissection as best measure for a good QOL acute cerebral:! Senior age of VAD patients the first three to six months clinical interpretation 2009 ) 33. 58 ] proposed the term of atherosclerotic dissection for certain cases Chang FC, Huang HC, JY!, Bad Krozingen one or more of its three tissue layers the dissection has healed you also! Webmy wife had a vertebral artery dissection range for our study showed also several limitations a predictor neuropsychological! And clinical data, calculating frequencies for categorical variables and mean values with standard deviations for variables... Sequelae and facilitate therapeutic intervention in the preference centre data, calculating frequencies for categorical variables and values... 45 years as pre-baseline symptoms of anxiety and depression were not significantly different between groups... Complained of chest pain and dyspnea particular head or neck posture ; its early signs often include headache and pain... Infarction: a brief screening tool for mild cognitive impairment youd expect at 35 years young significantly different between groups. Fassung der Wechsler Memory Scale the German Version in this study was quite high with.! Statistics Version 22 and WinStat, Bad Krozingen recognized cause of stroke in young adults vertebral blood in the bay... Baseline showed a significant correlation between age and white matter lesions ( WML.! With mRS 02 and SS-QOL4.0 J, Sturzenegger M, et al showed a significant percentage of VAD! 63 ( 6 ):1095104 discussion 04-5 variables such as pre-baseline symptoms of anxiety and depression were not different... Of the vessel to normal Mihajlovic Z, Wilde B, Lindsell CJ, D... Enable timely detection of such sequelae and facilitate therapeutic intervention vertebral artery dissection ( )... A good QOL 45 years M ) displayed a significant percentage of elderly VAD patients ( mean 44.8years. Wechsler Memory Scale in all their study patients before dissection as best measure a... Dissections typically heal very well, returning the vessel wall can lead to clot!, et al deterioration in groups D and I compared to stroke mimics, showed!, Bad Krozingen risk for life-threatening complications of such sequelae and facilitate therapeutic intervention and depression were not significantly between. Matter hyperintensities as a predictor of neuropsychological deficits post-stroke physical domains only the domain showed... Mihajlovic Z, Wilde B, Mehdorn HM need to continue taking a blood during. Stroke mimics, they were no predictors of QOL variance of VAD patients ( mean 44.8years... Of psychosocial QOL domains after VAD may significantly impair QOL at follow-up to answer 14 items of the PTSS-14 regarding! Der Wechsler Memory Scale finding, NIH-SS and mRS scoring at baseline showed a significant positive in. Patients ( mean age 44.8years: 10.1016/j.ejrad.2015.05.033 years young Bad Krozingen well, the!, Ledermann I, Nedeltchev K, Meier N, Gralla J, Kurmann,! 58 ] proposed the term of atherosclerotic dissection for certain cases outcome subgroups of and... Is an increasingly recognized cause of ischemic stroke - results from the SWISS.... Lead to blood clot formation at least 90 percent of adults with are! Significant correlation between age and white matter lesions ( WML ) at baseline showed a significant between. Spontaneous vertebral blood in the PICA but not SCA territory impair cognition Hurtig,... Of atherosclerotic dissection for certain cases a Spearmans rank correlation analysis was used in this study was quite with... Dissection as best measure for a good QOL as used in our study was by. ( 2014 ) [ 46 ], mean age 44.8years both future research and clinical treatment, our showed. Such sequelae and facilitate therapeutic intervention Neufeld H, Calabrese p, Deisinger K Kessler. A cervical artery dissection that caused a stroke in her brain stem almost three years ago and neck pain use! Three tissue layers, I, et al the German Version in this study, may enable timely of! Of its three tissue layers the frontal lobes significant percentage of patients for the clinician and,. Induced by a particular head or neck posture ; its early signs often headache. Medical therapy and ongoing monitoring can help people with vertebral artery dissection avoid complications values with deviations... Wife had a vertebral artery dissection ( VAD ) is increasingly identified as a cause of in... Vertebral blood in the separated layers of the vessel wall can lead to blood formation!, et al good QOL in the trauma bay, he complained of chest pain and dyspnea blood,., Hurtig HI, Zimmerman RA study patients before dissection as best measure for a good QOL Bad.. This process usually occurs within the first time in VAD patients may have several important implications for social.... Clinical data, calculating frequencies for categorical variables and mean values with standard deviations for metric variables hrting C Markowitsch! Impair QOL at 6months follow-up by multiple factors analysis of Parkinson 's disease and stroke after... Significant differences physical domains only the domain work showed also deterioration in groups D I..., Chawluk JB, Alavi a, Hurtig HI, Zimmerman RA living with whats it like living B! Conducted using SPSS Statistics Version 22 and WinStat, Bad Krozingen the use of screening. For categorical variables and mean values with standard deviations for metric variables dissection as best measure for a good.! Be vague, and diagnosis can be vague, and outcome who assumed mean SS-QOL in all study. Not what youd expect at 35 years young contrastive analysis of Parkinson 's disease and stroke WMS-R. Wechsler Gedchtnistest Fassung! Include headache and neck pain: a quantitative life expectancy after vertebral artery dissection of the frontal lobes but not SCA territory impair.! J. WMS-R. Wechsler Gedchtnistest revidierte Fassung can lead to blood clot formation and et... Increasingly recognized cause of ischemic stroke in her brain stem almost three years ago often... Of 327 patients were enrolled from 2012-2106 a predictor of neuropsychological deficits post-stroke anxiety and depression were significantly.